Vincent Brooks is unwilling to commit to marrying his longtime girlfriend Katherine.
One night at the Stray Sheep Bar, a drunken Vincent meets an enigmatic young woman named Catherine; they have a one-night stand which turns into an affair.
In addition to the Golden Playhouse mode, Babel Mode features four large stages playable with up to two players, while Colosseum features two players simultaneously playing a stage in order to reach the top first.
Set in an unnamed North American city, the plot of Catherine is presented as a story within a story on Golden Playhouse, a television program described as "like a Saturday morning theatre, with a bit of a Twilight Zone vibe".
Vincent must climb towers made of blocks, which Vincent must arrange into a stairway to reach the exit.
The stress of his double life and the growing intensity of his nightmares eventually compel Vincent to end the affair with Catherine.Catherine is a cross-genre video game in which players control Vincent Brooks, a man who is tormented by deadly nightmares after becoming involved with multiple women.The gameplay is divided into two parts; daytime social simulation segments where Vincent interacts with various characters at the Stray Sheep bar, and nightmare segments where he navigates deadly block towers using a combination of platforming and puzzle solving.If Vincent chooses to reconnect with Rin, she appears in Vincent's nightmare and is captured by Mutton, with Vincent rescuing her by defeating Astaroth.Alternate endings for Katherine and Catherine are unlocked if Vincent sends them a recording of Rin's piano music.